Muscle Cramps
A muscle cramp (charley horse) is a sudden, brief,
involuntary, painful contraction of a muscle or group of muscles. Cramps
commonly occur in healthy people (usually middle-aged and older people),
sometimes during rest, but particularly during or after exercise or at night
(including during sleep). Leg cramps at night usually occur in the calf and
cause plantar flexion of the foot and toes.
Other disorders can
simulate cramps:
·
Dystonias can cause muscle spasm, but symptoms
are usually more sustained and recurrent and involve muscles other than those
affected by typical leg cramps (eg, neck, hand, face, muscles throughout the
body).
·
Tetany can cause muscle spasm, but spasm is
usually more sustained (often with repetitive brief muscle twitches); it is
usually bilateral and diffuse, but isolated carpopedal spasm may occur.
·
Muscle ischemia during exertion in patients with
peripheral arterial disease (claudication) may cause calf pain, but this pain
is due to inadequate blood flow to muscles, and the muscles do not contract as
with a cramp.
·
Illusory cramps are the sensation of cramps in
the absence of muscle contraction or ischemia.
Etiology of Muscle
Cramps
The most common types of leg cramps are
Benign idiopathic leg cramps (leg cramps in the absence of a
causative disorder, typically at night)
Exercise-associated muscle cramping (cramps during or
immediately after exercise)
Although almost everyone has muscle cramps at some time,
certain factors increase the risk and severity of cramps. They include the
following:
·
Tight calf muscles (eg, due to lack of
stretching, inactivity, or sometimes chronic lower leg edema)
·
Dehydration
·
Electrolyte abnormalities (eg, low body levels
of potassium or magnesium)
·
Neurologic or metabolic disorders
·
Removal of a large volume of fluid during
dialysis in patients with end-stage kidney disease
·
Drugs
·
Also, certain toxins can cause muscle cramps.
Evaluation of muscle cramps focuses on recognition of what
is treatable. In many cases, a disorder contributing to cramps has already been
diagnosed or causes other symptoms that are more troublesome than cramps.
Cramps must be differentiated from claudication and
dystonias; clinical evaluation is usually adequate.
History
History of present illness should elicit a description of
cramps, including their duration, frequency, location, apparent triggers, and
any associated symptoms. Symptoms that may be related to neurologic or muscle
disorders can include muscle stiffness, weakness, pain, and loss of sensation.
Factors that can contribute to dehydration or electrolyte or body fluid
imbalances (eg, vomiting, diarrhea, excessive exercise and sweating, recent dialysis,
diuretic use, pregnancy) are recorded.
Review of systems should seek symptoms of possible causes,
including the following:
·
Amenorrhea or menstrual irregularity:
Pregnancy-related leg cramps
·
Cold intolerance with weight gain and skin
changes: Hypothyroidism
·
Weakness: Neurologic disorders
·
Pain or loss of sensation: Peripheral
neuropathies or radiculopathies
·
Past medical history should include any
disorders that can cause cramps. A complete drug history, including use of
alcohol, is taken.
Physical examination
General examination should include the skin, looking for
stigmata of alcoholism, nonpitting edema or loss of eyebrow hair (suggesting
hypothyroidism), and changes in skin moisture or turgor. A neurologic
examination, including deep tendon reflexes, is done.
Pulses should be palpated, and blood pressure measured in
all extremities. A weak pulse or low ankle:brachial blood pressure ratio in an
affected limb may indicate ischemia.
Red flags
The following findings are of particular concern:
Upper extremity or truncal involvement
Hyperreflexia or hyporeflexia
Muscle weakness
Fasciculations
Signs of alcoholism
Hypovolemia
Pain or loss of sensation in a peripheral nerve, plexus, or
root distribution
Interpretation of findings
Focal cramps suggest benign idiopathic leg cramps,
exercise-associated muscle cramping, musculoskeletal abnormalities, peripheral
nervous system causes, or an early degenerative disorder that can be
asymmetric, such as a motor neuron disorder.
Focal hyporeflexia suggests a peripheral neuropathy,
plexopathy, or radiculopathy.
In patients with diffuse cramps (particularly those who are
tremulous), hyperreflexia suggests a systemic cause (eg, ionized hypocalcemia;
sometimes alcoholism, a motor neuron disorder, or a drug, although effects on
deep tendon reflexes can vary by drug). Generalized hyporeflexia can suggest
hypothyroidism and sometimes alcoholism or be a normal finding, particularly in
older patients.
A normal examination and compatible history suggests benign
idiopathic leg cramps or exercise-associated muscle cramping.
Testing
Testing is done as indicated by abnormal clinical findings.
No tests are routinely done.
Blood glucose, renal function tests, and electrolyte levels,
including calcium and magnesium, should be measured if patients have diffuse
cramps of unknown cause, particularly if hyperreflexia is present.
Ionized calcium and arterial blood gases (ABGs) to confirm
respiratory alkalosis are measured if patients have tetany.
Electromyography is done if cramped muscles are weak.
MRI of the brain and often spinal cord is done if muscle
weakness or neurologic signs are focal.
Treatment of Muscle Cramps
Stretching
Underlying conditions are treated when identified.
If a cramp occurs, stretching the affected muscles often
relieves the cramp. For example, to relieve a calf cramp, patients can use
their hand to pull the toes and foot upward (dorsiflexion).
Applying heat (eg, using a warm towel or heating pad, taking
a warm bath or shower) or cold (eg, massaging the affected muscle with ice) may
help ease pain.
Prevention of Muscle Cramps
Measures to prevent cramps include the following:
·
Not exercising immediately after eating
·
Gently stretching the muscles before exercising
or going to bed
·
Drinking plenty of fluids (particularly
beverages that contain potassium) after exercise
·
Not consuming stimulants (eg, caffeine,
nicotine, ephedrine, pseudoephedrine)
·
Not smoking
·
The runner’s stretch is most useful. A person
stands with one leg forward and bent at the knee and the other leg behind and
the knee straight―a lunge position. The hands can be placed on the wall for
balance. Both heels remain on the floor. The knee of the front leg is bent
further until a stretch is felt along the back of the other leg. The greater
the distance between the two feet and the more the front knee is bent, the
greater the stretch. The stretch is held for 30 seconds and repeated 5 times.
The set of stretches is repeated on the other side.
Most of the drugs often prescribed to prevent cramps (eg,
calcium supplements, quinine, magnesium, benzodiazepines) are not recommended.
Most have no demonstrated efficacy. Quinine has been effective in some trials
but is no longer recommended because of occasional serious adverse effects (eg,
arrhythmias, thrombocytopenia, thrombotic thrombocytopenic purpura [TTP] and
hemolytic-uremic syndrome [HUS], severe allergic reactions). Mexiletine
sometimes helps, but whether using it is worth the risk of adverse effects is
unclear. These effects include nausea, vomiting, heartburn, dizziness, and
tremor.
Some athletic coaches and physicians recommend pickle juice
for muscle cramping, but data concerning its efficacy are insufficient.read more...........
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